教师简介：

一、基本情况

姓     名：李秦瑾

性     别：女

政治面貌：中共党员

职    称：讲师

职    务：无

研究方向：脂肪肝疾病与脂质代谢的基础研究

联系电话：13971387834

电子邮箱：liqinjin0809@163.com

二、受教育经历

2020.09-2024.06 华中农业大学 基础兽医学 博士

2017.09-2020.06 华中农业大学 生物化学与分子生物学 硕士

2013.09-2017.06 湖北大学 生物技术 本科

三、研究工作经历

2024.09-至今 bat365在线官网平台，讲师

四、科研成果

主要从事脂肪肝疾病与脂质代谢的基础研究。发表论文共7篇，其中第一作者或共同第一作者发表论文4篇，以共同参与作者发表论文3篇。

五、代表性论文与著作

1. Li, Q., Pan, Y., Zhang, J., Hu, B., Qin, D., Liu, S., Chen, N., and Zhang, L. TET2 regulation of alcoholic fatty liver via Srebp1 mRNA in paraspeckles. iScience, 2024, 27(3): 109278.

2. Li, Q., Gong, Y., Wang, Y., Liu, B., Chu, Y., Gui, S., Zheng, Y., and Chen, X. Sirt1 Promotes the Restoration of Hepatic Progenitor Cell (HPC)-Mediated Liver Fatty Injury in NAFLD Through Activating the Wnt/beta-Catenin Signal Pathway. Front Nutr, 2021, 8: 791861.

3. Zhou, L# , Li, Q# , Chen, A# , Liu, N., Chen, N., Chen, X., Zhu, L., Xia, B., Gong, Y., and Chen, X. KLF15-activating Twist2 ameliorated hepatic steatosis by inhibiting inflammation and improving mitochondrial dysfunction via NF-kappaB-FGF21 or SREBP1c-FGF21 pathway. FASEB J, 2019, 33(12): 14254-14269.

4. 李秦瑾，陈小冬. 动物成肌分化及非编码 RNA 调控研究进展. 中国畜牧杂志, 2019, 55(11):6.

5. Liu, B., Chen, D., Wang, Y., Li, Q., Zhu, L., Yang, Z., and Chen, X. Adipose improves muscular atrophy caused by Sirtuin1 deficiency by promoting mitochondria synthesis. Int J Biochem Cell Biol, 2022, 149: 106246.

6. Zhu, L., Li, B., Chen, D., Chen, N., Xu, L., Li, Q., and Chen, X. sSTEAP4 regulates cellular homeostasis and improves high-fat-diet-caused oxidative stress in hepatocytes. Life Sci, 2022, 296: 120438.

7. Zhu, D., Xu, L., Wei, X., Xia, B., Gong, Y., Li, Q., and Chen, X. PPARγ enhanced Adiponectin polymerization and trafficking by promoting RUVBL2 expression during adipogenic differentiation. Gene, 2021, 764: 145100.